Evidence
Proof, not promises.
Every active ingredient, the daily amount the trial used, and what that trial found, including where results were modest or general-population. Each result belongs to the ingredient, not to the finished blend. Batch test results are published below.
AllMoodEveryday stressSleepComfortHormone levels
| Ingredient | Dose studied | Participants | Design | Finding | |
|---|---|---|---|---|---|
| Saffron extract | 28mg/day (14mg twice daily) | 82 · 12 weeks Perimenopausal women | Randomised, placebo-controlled | Greater improvement than placebo on the psychological cluster of menopausal symptoms (anxiety and depressive-mood scores). No separation from placebo on hot flashes. | |
| Lavender oil (oral) | 80mg/day | 1200 · 10 weeks Adults with subthreshold anxiety (pooled) | Meta-analysis of 5 placebo-controlled trials | Anxiety scores fell about 2.9 points more than placebo on the Hamilton scale. General-population evidence, not menopause-specific. | |
| Maritime pine bark extract | 60mg/day (30mg twice daily) | 170 · 12 weeks Menopausal women | Randomised, placebo-controlled | Overall menopausal symptom index improved more than placebo. Estradiol, FSH, and other hormone levels were measured and did not change versus placebo. | |
| L-Theanine | 200mg/day | 30 · 4 weeks Healthy adults | Randomised, placebo-controlled crossover | Better self-reported sleep quality and lower stress scores. General-population evidence. | |
| Lavender oil (oral) | 80mg/day | 24 · 3 weeks Women taking an oral contraceptive | Pharmacokinetic interaction study | No interference with an ethinyl-estradiol oral contraceptive. Substantiates that oral lavender oil does not act on estrogen. |
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
Third-party tested
Every batch, one PDF.
Heavy metals, microbials, and label-claim verification by an independent lab. Results posted here before the batch ships.
Manufacturing
cGMP, designed in Utah.
Made in an FDA-registered, cGMP facility. No soy, no phytoestrogens, no hormones, and no ingredient that acts on your estrogen.
What we don't claim
It is not a cure.
Liesse helps support mood, calm, comfort, and sleep quality. It does not treat menopause and it does not replace hormone therapy. If a product tells you otherwise, ask for its study.